The Top 20 Pharmaceutical Companies in the U.S. in 2019 by Market Cap

When it comes to determining the largest Pharmaceutical companies, the ranking of one company can go up or down from one year to the next. This is particularly when assigning the status of the company by its market capitalization, also known as market cap value. The biggest reason for this is because of the hundreds of mergers and acquisitions that take place at any given point in time. This can drastically change the market cap and it’s a consideration to be made when ranking the top businesses. We’ve looked into the top performers and have put together a ranked list of the top 20 pharmaceutical companies in the United States for 2019, in accordance with their market cap, beginning with the 20th and moving forward to the 1st.

20. Cardinal Health Inc. – $14.04 billion

Cardinal Health, Inc. is a United States-based pharmaceutical company which is the 20th largest in the nation. It is listed on the New York Stock Exchange and has a world ranking of 952. Cardinal is listed as CAH on the exchange. It’s a globally integrated healthcare products and services provider. The company distributes and markets medical and pharmaceutical products as well as providing customized solutions for health systems, pharmacies, ambulatory surgery centers, hospitals, physicians offices, and clinical laboratories throughout the world. The company manufactures surgical products and medicines, they conduct home deliveries and they own several pharmacies.

19. Biomarin Pharmaceutical Inc – $15.34 billion

This company is the 19th largest by market cap in the United States and the 875th in its world ranking as of July 2019. It is headquartered in California, United States and is listed on the NASDAQ exchange. Biomarin is a biotechnology and pharmaceutical company which manufactures and distributes healthcare products.

18. AmerisourceBergen Corporation – $17.92 billion

AmerisourceBergen Corporation is a Holding Company which focuses upon the distribution of medicine and pharmaceutical products. It is headquartered in the United States and is listed on the New York Stock Exchange. They own over 3,000 pharmacies. They’re the 18th largest pharmaceutical company in the USA and ranked as the 771st largest in the world.

17. INCYTE Corporation – $18.22 billion

Incyte Corporation is ranked number seventeen in market cap size in the US and number 759 in its world ranking. It is listed on the NASDAQ Stock Exchange. The company is based in the United States and it is concerned with clinical research into the discovery and development of new drugs which will be effective in fighting cancer and other diseases. The company maintains a team of development scientists and has achieved a proven track record of success in scientific and clinical discoveries and development. Incyte manufactures and distributes healthcare and pharmaceutical products.

16. McKesson Corporation – $25.05 billion

The McKesson Corporation is the 16th largest pharmaceutical company in the United States as of July 1, 2019. The company has a market capitalization of $25.05 billion and is ranked as the 553rd largest pharmaceutical company in the world. It climbed nearly 30 spaces on the world ranking between March of 2019 and July of the same year. The company is listed on the New York Stock Exchange and is headquartered in New York, USA. This company is the sixth largest and the oldest of its kind in the country. It serves 20% of the physicians in the US and 50% of the hospitals with medications, and healthcare services and products. McKesson also owns over 2,000 pharmacies and they operate within 16 countries throughout the world.

15. Alexion Pharmaceuticals Inc – $29.37 billion

Alexion Pharmaceuticals Inc is the fifteenth largest pharmaceutical company in the US as of July 2019. It is ranked as the 467th largest in the world. Alexion is listed on the NASDAQ Stock Exchange and is headquartered in the state of Connecticut in the United States of America. They manufacture and distribute healthcare and pharmaceutical products.

14. Regeneron Pharmaceuticals Inc – $34.32 billion

The fourteenth-largest pharma company in the US is ranked as number 400 in the world as of July of 2019. It was previously the 263rd largest in the world but was moved down the list due to a falling market cap. This company is headquartered in the United States and it is listed on the NASDAQ Stock Exchange. They are involved with the research, development, and production of healthcare and pharmaceutical products

13. Baxter International Inc. – $41.78 billion

Baxter International Inc is the thirteenth-biggest pharmaceutical company in the United States as of July of 2019. It is also ranked as the 301st largest in the world. This company is listed on the New York Stock Exchange. Baxter International Inc is concerned with the development of medical devices and healthcare products which are associated with immunity disorders and kidney diseases. They are headquartered in the United States.

12. Vertex Pharmaceuticals Incorporated – $46.97 billion

Vertex Pharmaceuticals Incorporated is the twelfth-biggest pharmaceutical company in the United States for 2019 by market capitalization as a determinant of size. The company ranks number 259 in the world ranking. Vertex is headquartered in the United States and is listed on teh NASDAQ Stock Exchange. It is a biotechnology, Biopharmaceutical, and Healthcare company specializing in the development and manufacture of healthcare products and pharmaceuticals.

11. Zoetis Inc – $54.32 billion

Zoetis Inc is a United States of America based pharmaceutical company that ranks 11th largest in the USA by market cap, and number 212 in its world ranking. It’s listed on the New York Stock Exchange and manufactures medicine and vaccinations or animals.

10. Shire PLC – $57.62 billion

Shire PLC is the tenth-largest US-based pharmaceutical company, and it is ranked number in its world ranking, falling from number 187 from March 2019 to July of the same year. This company is listed on the LSE Stock Exchange and is headquartered in the USA. this is a biopharmaceutical company that manufactures biopharmaceuticals, healthcare products, and pharmaceuticals.

9. Celgene Corporation- $65.19 billion

Celgene Corporation is the ninth-largest pharmaceutical company in the US as of July 2019, rising from its previous March 2019 market cap of $44.8 billion. It is ranked as the 166th largest in the world, moving up two positions since March of 2019. Celgene Corporation is headquartered in the United States and listed on the NASDAQ Stock Exchange. It is a global biopharmaceutical company with a focus on discovery, development, and commercialization of healthcare and pharmaceutical products for the treatment of immune, inflammatory and cancerous conditions which are severe.

8. Bristol-Myers Squibb – $74.18 billion

Bristol-Myers Squibb is the 8th largest pharmaceutical company in the US with a market cap of $74.18 billion, which is down by a little over $10 billion between December of 2018 and July of 2019. BMS is ranked as number 139 in the world s of July 2019, dropping from its previous spot of number 121 since March of this year. The company is headquartered in the US and is listed on the New York Stock Exchange. The company employs 23,700 workers. It is a global biopharmaceutical company focused on discovery, development, and delivery of medicines aimed at fighting serious diseases.

7. AbbieVie Inc. – $107.51 billion

AbbieVie Inc has dropped from a market cap of $139.6 billion to $107.51 billion between December of 2018 and July of 2019. It’s the 7th largest pharmaceutical company in the US and the 89th largest in the world by market cap. This company is based in the United States and is listed on the New York Stock Exchange. It employs 29,000 workers and it’s a multi-national company that is involved with scientists, researchers, and communicators who discover and develop pharmaceutical and healthcare products. They also manufacture and distribute these products all over the world.

6. Eli Lilly and Company – $107.56 billion

Eli Lilly and Company is the sixth-largest pharmaceutical company in the United States and it is ranked as the 88th largest in the world as of July 1, 2019. It is listed on the New York Stock Exchange. Eli Lilly concerns itself with the business of researching and developing bio-medicines, treatments in oncology and diabetes in humans and in animal pharmaceutical and healthcare product manufacturer. The company employs 41,000 workers. The company previously had a market cap of $122.6 billion in December of 2018 and has dropped between that time and July of 2019.

5. Amgen Inc. – $124 billion

Amgen Inc is the fifth-largest pharma company in the USA. In December of 2018, the market cap was $124.40 billion. The company dropped $12 billion in its MC between this time and July of 2019. It is currently ranked the 82nd largest pharma company in the world. Amgen is headquartered in the United States and listed on the NASDAQ stock exchange. The company is a leader in the biotech industry and is involved in the research, development, and production of biotech products. It employs more than 2,000 workers. The key focuses of work for Amgen is in the areas of fighting heart disease, cancer and the prevention of infections as well as campaigns to enhance patient-provider conversations. Amgen employs 20,000 workers.

4. Abbott Laboratories $148.37 billion

Abbot Laboratories had a market cap of $127 billion in December of 2018. The company’s market cap has grown to $148.37 billion between December 2018 and July 1 of 2019. It is the fourth-largest pharmaceutical company in the United States and ranked number 58 in the world. It climbed one spot in world ranking between March and July of 2019. Abbott Laboratories is registered with the New York Stock Exchange and it is headquartered in the United States, but it is a multi-national company with a presence in over 150 countries throughout the world, employing over 99,000 workers. The primary work they perform is involved with the diagnosis of diabetes, nutrition, neuromodulation, and pharmaceuticals.

3. Merck & Co – $215.88 billion

Merck & Co. is the third-largest pharmaceutical company in America, and it is ranked as the 33rd largest in the world. The company had a market cap of $198.7 billion on December 31, 2018, and it hs since grown to $215.88 s of July 1, 2019. It is listed on the New York Stock Exchange and the company is involved in healthcare and pharmaceutical development and manufacture. This is a company that is based in the United States, but it operates on a global level to deliver medicines and vaccines for humans as well as animal health products. Merck & Co. employs 69,000 workers throughout the world.

2. Pfizer – $240.86 billion

Pfizer Inc realized a market cap of $240.86 billion in July of 2019, dropping from its previous market cap of 253.2 billion on December 31, 2018. It is the second-largest pharmaceutical company in the United States as of July of 2019, and it is ranked 23rd in the world. The company is listed on the New York Stock Exchange. The company is headquartered in New York. It manufactures medicines and other products as well as overseeing over 500,000 lab tests. Pfizer is also involved with more than 36 clinical trials which are conducted prior to medications and treatments are prescribed. The company develops medicines for diseases which range from simple in nature to more complicated. They employ 1,500 scientists on the staff. ​​​​​​​

1. Johnson & Johnson – Market cap $369.80 billion

Johnson & Johnson is the number one ranked pharmaceutical company in the United States as of July 1, 2019. Its ranking in the world is number 10 as of July of 2019, having dropped one place since March of the same year. This company is listed on the New York Stock Exchange. The company is based in the United States and is involved in the manufacture of consumer goods, medical equipment and devices, and pharmaceutical products. The company operates in 60 different countries throughout the world and it employs 125, 000 workers.

Statistics from the following sources were used to make comparisons of the market capitalization values from 2018 through July of 2019. The figures were compared and the companies have been ranked in accordance with updated and current market values. Each of these resources was helpful in looking back at the history and profiles of the companies for the most up to date rendering and ranking of the top 20.

References

Beckers Hospital Review, Investopedia, Value Today, Global Data